Cooling Agent WS-3 | N-Ethyl-p-menthane-3-carboxamide

Cooling Agent WS-3 Product Overview
What Is Cooling Agent WS-3?
Cooling Agent WS-3 is a food-grade synthetic cooling agent. Its chemical name is N-Ethyl-p-menthane-3-carboxamide. It comes from the menthol family, yet it behaves very differently from menthol in most formulas.
Third, Cooling Agent WS-3 carries a long record of food use, and it holds FEMA number 3455. It also carries CAS number 39711-79-0. Consequently, formulators around the world treat it as the standard choice for clean, long-lasting mouth cooling.
Cooling Performance Profile
Unlike menthol, WS-3 brings no burning, no stinging and no numbing effect. In other words, it delivers a clean sensation. Moreover, it supports your existing flavor instead of competing with it.
For example, at 30 to 100 mg/kg in a still beverage, the cooling becomes clear and easy to notice. However, WS-3 also stays stable at temperatures up to 200 °C. Therefore, it survives baking, pasteurization and UHT processing without any loss of strength. Nevertheless, we still suggest a short stability trial for each new formula.
Production & Quality
Our GMP-aligned plant in Xi’an produces Cooling Agent WS-3 from carefully selected raw materials.
We test every incoming batch before production. Approved material then moves into a controlled synthesis line. Meanwhile, our operators keep temperature, pressure and reaction time inside tight limits. After that, we crystallize, dry and mill the product in a clean environment.
Our quality team checks each lot by HPLC and GC. In addition, we release a Certificate of Analysis with every shipment. Because of this, our customers enjoy consistent purity, consistent particle size and consistent cooling strength, lot after lot.
Why Choose Our Cooling Agent WS-3?
Cooling Agent WS-3 comes in two practical forms, so you can pick the one that fits your production line.
The crystalline powder suits dry blends, chewing gum, candy, toothpaste and instant sachets. Meanwhile, our pre-dissolved liquid blend flows easily into beverages, mouthwash and e-liquid formulas. Moreover, it saves you a dissolution step.
We also keep order quantities flexible. What is more, a trial order can start at 1 kg, while bulk orders ship in 25 kg fiber drums without any change to the base specification.
Each shipment includes a Certificate of Analysis (COA). In addition, we can supply MSDS, TDS, allergen statements and third-party test reports whenever you need them.
Finally, our technical team helps you match the dosage to your formula. As a result, the cooling lands exactly where you want it and nowhere else.

Technical Specifications
| Item | Specification |
| Product Name (EN) | Cooling Agent WS-3 |
| Chemical Name | N-Ethyl-p-menthane-3-carboxamide |
| Synonyms | WS-3; Ethyl Menthane Carboxamide; N-Ethyl-2-isopropyl-5-methylcyclohexanecarboxamide |
| CAS Number | 39711-79-0 |
| FEMA Number | 3455 |
| EINECS Number | 254-599-0 |
| Molecular Formula | C13H25NO |
| Molecular Weight | 211.34 g/mol |
| Appearance | White crystals / crystalline powder |
| Odor | Practically odorless, with a faint cooling note |
| Taste | Neutral; delivers cooling without bitterness |
| Assay (Purity) | >= 99.0% (HPLC) |
| Melting Point | 87 – 102 °C |
| Flash Point | > 200 °C |
| Solubility | Soluble in ethanol, propylene glycol and other food-grade solvents; slightly soluble in water (< 0.1%) |
| Cooling Duration | 15 – 30 minutes |
| Recommended Dosage | Beverage 1-10 mg/kg; candy 15-150 mg/kg; chewing gum 500-2000 mg/kg; toothpaste 100-1000 mg/kg; mouthwash 5-200 mg/kg; cream and lotion 500-5000 mg/kg |
| Heat Stability | Stable up to 200 °C |
| Category | Cooling Agents |
| Storage Conditions | Store in a cool, dry place. Keep away from direct light and heat. Close the package tightly after use. |
| Shelf Life | 24 months when stored properly |
Applications & Uses
Oral Care Applications
Cooling Agent WS-3 can add a clean, lasting coolness to:
- Toothpaste and whitening gel
- Mouthwash and breath freshener
- Chewing gum and bubble gum
- Dental floss and dental gel
- Breath strips and oral sprays
- Lozenges and oral analgesics
Beverage & Confectionery Applications
The cooling agent also performs well in:
- Sparkling water and flavored soda
- Iced tea and ready-to-drink beverages
- Energy drinks and sports drinks
- Beer and distilled spirits
- Hard candy and chewy candy
- Gummies and jelly
- Chocolate and compound coatings
- Ice cream, sorbet and frozen dessert
- Syrups and cordials
Cosmetics & Personal Care Applications
Personal care formulators commonly add WS-3 to:
- Skin cream and body lotion
- Face mask and cooling gel
- Shaving cream and after-shave
- Shampoo and scalp care
- Sunscreen and after-sun lotion
- Shower cream and soap
- Lip balm
- Air freshener
- Insect-repellent formulation
Pharmaceutical & Specialty Applications
WS-3 also supports:
- OTC liniments and cooling balms
- Cooling patches and plasters
- Throat lozenges and cough drops
- Nicotine pouches and oral nicotine products
- E-liquids and vape formulas
- Cigarette filters and tobacco products
- OEM flavor and cooling blends
Certifications & Compliance
We can provide the following quality and product documents:
- ISO 9001:2015 — Quality Management System
- ISO 22000 — Food Safety Management
- GMP — GMP-aligned manufacturing facility
- HALAL — Certified batches available
- KOSHER — Certification available upon request
- COA / MSDS / TDS — Product documents available for each lot
- FEMA 3455 / REACH — Regulatory and compliance support
- Non-Restricted Cargo — Standard export classification
- Third-party laboratory testing — SGS, Eurofins or your selected laboratory
Packing & Logistics
Standard Package
Powder: 1 kg / aluminium-foil bag; 25 kg / fiber drum.
Liquid blend: 1 kg / bottle; 5 kg and 25 kg / drum.
Carton Dimensions
22 cm × 16 cm × 34 cm
Packaging Material
We pack the crystalline powder in food-grade aluminium-foil bags. We then place the bags inside strong cardboard cartons or HDPE-lined fiber drums. The liquid blend goes into food-grade HDPE bottles and drums.
Sealing
We seal each package with three layers of tape winding and shock-resistant packing.
Net Weight
1 kg per standard package.
Custom package sizes such as 5 kg and 25 kg are available upon request.
Frequently Asked Questions
What is Cooling Agent WS-3, and how does it cool?
Cooling Agent WS-3 is N-Ethyl-p-menthane-3-carboxamide, a synthetic cooling agent with CAS number 39711-79-0. It activates the TRPM8 cold receptor on the tongue. As a result, you feel cold without any real temperature change. The effect lasts 15 to 30 minutes.
How does WS-3 differ from WS-23 and from menthol?
Menthol is volatile, and it carries a strong mint aroma with some bitterness. WS-3 stays non-volatile and practically odorless, so it cools without flavor interference. On the other hand, WS-23 gives a sharper, front-loaded burst. In contrast, WS-3 offers a rounder, longer-lasting coolness. Therefore, many formulators combine the two to build a layered cooling profile.
What dosage should I use in my product?
Typical doses run from 1 to 10 mg/kg in beverages. For candy, the range runs 15 to 150 mg/kg. Toothpaste uses 100 to 1000 mg/kg, and chewing gum uses 500 to 2000 mg/kg. Specifically, our technical team can fine-tune the level for your formula.
Can you provide samples and a COA?
Yes. We supply 10-50 g samples for R&D work. In addition, we send a Certificate of Analysis with every lot. If you need extra testing, we arrange it through SGS, Eurofins or another laboratory of your choice.
Do you offer OEM blends and private-label service?
Yes. We build custom cooling blends, pre-dissolved liquid versions and private-label packaging. Consequently, you can launch a product under your own brand.
What are the lead time and payment terms?
Stock items usually ship within 48-72 hours after order confirmation. However, custom blends normally take around 10-15 days. Even so, we always confirm the schedule in writing before production starts. We accept T/T, L/C, D/P and other common payment methods.
Need specifications, COA, or a wholesale quote? Contact Us — typical response within 24 hours.
