News & Insights

Cooling Agents in Cough Syrup and Pharmaceutical Formulations

By Baisifu Cooling Agents Division
Cooling agent WS-12 for cough syrup and pharmaceutical formulations
Cooling agents in cough syrup and pharma
❄ WS · NEWS

Why pharma formulators choose WS-10 and WS-3 for syrups, throat sprays and lozenges: tasteless cooling, TRPM8 activity and batch COA.

Cooling in pharmaceutical products does two jobs at once: it delivers a genuine sensory benefit the patient feels immediately, and it masks the bitterness of active ingredients without adding sugar or strong flavor.

In cough syrups and liquid medicines, WS-10 (menthoxypropanediol) is the workhorse – fully soluble, essentially tasteless, and stable in aqueous systems. In throat sprays and lozenges, WS-3 provides a clean cooling that soothes on contact, with TRPM8-mediated activity and no numbing.

Every batch ships with a COA suitable for pharma vendor qualification, and our team provides solubility and stability guidance for your specific vehicle. Cooling that comforts – and documentation your QA department will accept.

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